SYMPLICITY HTN-3 results to be announced: a mystery or a story foretold?
نویسندگان
چکیده
a Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven 3000, Belgium; Pole of Cardiovascular Research, Institut de Recherche Experimentale et Clinique, Universite Catholique de Louvain, Brussels 1200, Belgium; c Division of Cardiology, Cliniques Universitaires Saint-Luc, Universite Catholique de Louvain, Brussels 1200, Belgium. Received 03 January 2014, Accepted 15 January 2014, Epub 20 February 2014
منابع مشابه
Resistant hypertension and renal denervation. Considerations on the results of the SYMPLICITY HTN-3 trial.
Resistant hypertension is undoubtedly a real clinical challenge, given that it increases cardiovascular events and has no effective treatment. Thus, it is easy to see why renal sympathetic denervation (RDN) has raised expectations among physicians treating patients with this serious disease. The SYMPLICITY HTN-1 trial was a proof-of-principle trial followed by the SYMPLICITY HTN-2 trial, which ...
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UNLABELLED High nighttime and early morning blood pressure (BP) have been associated with greater risk for cardiovascular events than high clinic or daytime BP. BP is typically highest in the rising hours, when morning activities typically begin. We examined the effect of renal denervation on morning (6:00-8:59 AM), daytime (9:00 AM-8:59 PM), and nighttime (1:00-5:59 AM) ambulatory BP. Patient ...
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Ever since Schlaich et al.1 first reported on a patient with a blood pressure of 161/107 mm Hg (despite treatment with seven different antihypertensive drugs) that decreased to 127/81 mm Hg after renal denervation, the medical community has been enamored with this procedure. Resistant hypertension evolved into a fashionable diagnosis, and the number of publications pertaining to it grew rapidly...
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